Specification
Product name CRP Antibody
Immunogen Recombinant full-length protein.
Source/Isotype Mouse IgG1Kappa
Reactivity Human
Purification Protein G purified from hybridoma culture supernatant
Application ELISA, others unspecified
Form Liquid
Storage Buffer In 1?PBS, pH 7.2
Storage Instruction Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at - 20°C or lower long term. Aliquot to avoid repeated freezing and thawing.
Concentration 5.2mg/mL
Lot 20231013
Size 1000μg
UniProt ID P02741
Entrez-Gene Id 1401
Protein Name C-reactive protein
[1]Inflammation is a kind of defense reaction of the body to various pathogens and tissue damage, and it is a protective factor of the body. However, excessive inflammatory response will aggravate tissue damage and cause a series of clinical complications and adverse consequences. C-reactive protein (CRP) is synthesized by liver cells, produced during fetal life and not transmitted by the maternal placenta. The mechanism of its production is that when the body is infected or the tissue is damaged, macrophages and other white blood cells are activated to produce cytokines such as interleukin-6 (IL-6), interleukin-1 (IL-1), tumor necrosis factor TNF-a and other mediators, which reach the liver and stimulate the synthesis of CRP by liver cells and epithelial cells. Structurally, CRP contains 5 polypeptide chain subunits, non-covalently bound to a disk polymer with a molecular weight of 115,000-140,000, CRP is a typical acute phase protein.
[2]蔣雪梅,頓耀艷,倪毅然,等. 炎癥成分與相關(guān)系統(tǒng)疾病的研 究[J/CD].世界最新醫(yī)學(xué)信息文摘 ( 連續(xù)型電子期刊) ,2015,15( 65) : 35-36.
[3]段玲.CRP檢測對急性胰腺炎嚴(yán)重程度及壞死程度的評估價(jià) 值[J].中華胰腺病雜志,2016,16( 4) : 264-266.
[4]Ishida S,Hashimoto I,Seike T,et al. Serum albumin levels correlate with inflammation rather than nutrition supply in burns patients: A retrospective study[J]. J Med Invest,2015,61( 3 /4) : 361-368
[5]Nourimajalan N,Masoumi R,Halvani A,et al. Lung contusion and cavitation with exudative plural effusion following extracorporeal shock wave lithotripsy in an adult: A case report[J].J Med Case REP,2010,4( 1) : 1-3.
[6]C反應(yīng)蛋白測定試劑盒注冊技術(shù)審查指導(dǎo)原則.
Product Cat. Description
CRP Antibody RYZ004AB4B-0001 ELISA, others unspecified.
CRP Antibody RYZ004AB6B-0001 ELISA, others unspecified.
CRP Antibody RYZ004AB11B-0001 ELISA, others unspecified.
CRP Antibody RYZ004AB9B-0001 ELISA, others unspecified.
CRP Antibody RYZ004AB12B-0001 ELISA, others unspecified.
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